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ESTRADIOL®
Estradiol® is an oral hormone, used to reduce
the symptoms of menopause (hot flashes, feelings
of warmth in the face, neck and chest and/or dry,
itchy external genitals and vaginal irritation.
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Estradiol®
Important Note about Estradiol:
The following information is intended to supplement,
not substitute for, the expertise and judgment of your
physician, pharmacist or other healthcare professional.
It should not be construed to indicate that use of the
drug is safe, appropriate, or effective for you. Consult
your healthcare professional before using Estradiol.
Estradiol Warning:
Estradiol has been reported to increase the
chance of womb (endometrial) cancer in women who have been through
menopause. This risk appears to depend on the length of time Estradiol
is used and the amount of estrogen per dose. If you use Estradiol for
an extended period, you should be evaluated at least every 6 months. If
you experience abnormal vaginal bleeding on Estradiol, notify your
doctor promptly. Estradiol is not effective in preventing or treating a
tendency toward miscarriages (natural habitual abortion) nor the threat
of miscarriage. Estradiol must not be used during pregnancy because its
use may result in birth defects or cancer later in the child's life. If
you become pregnant or think you may be pregnant, consult your doctor
immediately to discuss the risk to the fetus.
Uses of Estradiol:
Estradiol is a hormone and is given to women who
no longer produce the proper amount. Estradiol is used to reduce
menopause symptoms (e.g., hot flashes), for brittle
bones (osteoporosis), and Estradiol treats certain cancers in
both men and women.
How to Use Estradiol:
Estradiol may be taken with food or immediately after a meal to
prevent stomach upset. Take Estradiol as prescribed.
Follow the dosing schedule carefully. Be sure to ask
your doctor if you have any questions about Estradiol.
Estradiol Side Effects:
May cause dizziness, lightheadedness, headache, stomach
upset, bloating, or nausea. These effects should disappear
as your body adjusts to Estradiol. Notify your
doctor if you experience: severe depression, calf pain,
sudden severe headache, chest pain, shortness of breath,
lumps in the breast, weakness or tingling in the arms
or legs, yellowing of the eyes or skin, changes in vaginal
bleeding (spotting, breakthrough bleeding, prolonged
or complete stoppage of bleeding), stomach pain, skin
rash. If you notice other effects not listed above while taking Estradiol,
contact your doctor or pharmacist.
Estradiol Precautions:
Before you take Estradiol, tell your doctor
your entire medical history, including: family medical history
(especially breast lumps and cancer), high blood pressure, diabetes,
asthma, epilepsy (seizures), migraine headaches, liver disease, heart
disease, kidney disease, depression, toxemia (high blood pressure
during pregnancy), jaundice (yellowing skin/eyes) during pregnancy,
excessive weight gain and fluid retention (bloating) during menstrual
cycle, uterine fibroid tumor, abnormal vaginal bleeding, blood clots or
stroke, cholesterol or lipid problems, gallbladder disease. Before
having surgery, tell the doctor that you take Estradiol. Depending on
strength, Estradiol may cause a patchy, darkening of the skin on the
face (melasma). Higher strengths are more likely to cause melasma.
Sunlight may intensify this darkening and you may need to avoid
prolonged sun exposure and sunlamps. Consult your doctor regarding use
of sunscreens and protective clothing. Cigarette smoking can increase
the chance of blood-clots while taking Estradiol (especially in
women past the age of 35). Estradiol should not be used during
pregnancy. If you become pregnant or think you may be pregnant, inform
your doctor immediately. Estradiol may be excreted into breast milk and
its use is not recommended while breast-feeding. Consult your doctor
before breast-feeding.
Drug Interactions of Estradiol:
Tell your doctor of all prescription and nonprescription
drugs you may use, especially of: hydantoins (e.g.,
phenytoin), barbiturates (e.g., phenobarbital), corticosteroids
(e.g., prednisone). Estradiol can affect the results
of certain lab tests. Make sure laboratory personnel
and your doctors know you use Estradiol. Do not start
or stop any medicine without doctor or pharmacist approval.
Estradiol Overdose:
If Estradiol overdose is suspected, contact your local poison
control center or emergency room immediately. Symptoms
of Estradiol overdose may include nausea/vomiting or stoppage
of periods.
Notes about Estradiol:
Do not share Estradiol with others.
Estradiol Missed Dose:
If you miss a dose of Estradiol, take as soon as remembered; do not
take if it is almost time for the next dose, instead,
skip the missed dose and resume your usual dosing schedule.
Do not "double-up" the dose to catch up.
Storage of Estradiol:
Store Estradiol at room temperature between 59 and 86 degrees
F (between 15 and 30 degrees C) away from moisture and
sunlight. Do not store Estradiol in the bathroom.
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